阪大消化器内科のご紹介・研究実績



2007年

  1. Takehara T, Uemura A, Tatsumi T, Suzuki T, Kimura R, Shiotani A, Ohkawa K, Kanto T, Hiramatsu N, Hayashi N.
    Natural killer cell-mediated ablation of metastatic liver tumors by hydrodynamic injection of IFNα gene to mice.
    Int J Cancer 120: 1252-1260, 2007.
  2. Jinushi M, Takehara T, Tatsumi T,Yamaguchi S, Sakamori R, Hiramatsu N, Kanto T, Ohkawa K, Hayashi N.
    Natural killer cell and hepatic cell interaction via NKG2A leads to dendritic cell-mediated induction of CD4+ CD25+ T cells with PD-1-dependent regulatory activities.
    Immunology 120: 73-82, 2007.
  3. Tatsumi T, Takehara T, Yamaguchi S, Sasakawa A, Sakamori R, Ohkawa K, Kohga K, Uemura A, Hayashi N.
    Intrahepatic delivery of α-galactosylceramide-pulsed dendritic cells suppresses liver tumor.
    Hepatology 45: 22-30, 2007.
  4. Miyatake H, Kanto T, Inoue M, Sakakibara M, Kaimori A, Yakushijin T, Itose I, Miyazaki M, Kuzushita N, Hiramatsu N, Takehara T, Kasahara A, Hayashi N.
    Impaired ability of interferon-alpha-primed dendritic cells to stimulate Th1-type CD4 T-cell response in chronic hepatitis C virus infection.
    J Viral Hepat 14: 404-412, 2007.
  5. Tatsumi T, Takehara T, Yamaguchi S, Sasakawa A, Miyagi T, Jinushi M, Sakamori R, Kohga K, Uemura A, Ohkawa K, Storkus WJ, Hayashi N.
    Injection of IL-12 gene-transduced dendritic cells into mouse liver tumor lesions activates both innate and acquired immunity.
    Gene Ther 14: 863-871, 2007.
  6. Itose I, Kanto T, Inoue M, Miyazaki M, Miyatake H, Sakakibara M, Yakushijin T, Oze T, Hiramatsu N, Takehara T, Kasahara A, Katayama K, Kato M, Hayashi N.
    Involvement of dendritic cell frequency and function in virological relapse in pegylated interferon-alpha and ribavirin therapy for chronic hepatitis C patients.
    J Med Virol 79: 511-521, 2007.
  7. Irie T, Tsujii M, Tsuji S, Yoshio T, Ishii S, Egawa S, Kakiuchi Y, Nishida T, Yasumaru M, Iijima H, Murata H, Takehara T, Kawano S, Hayashi N.
    Synergistic antitumor effects of celecoxib with 5-fluorouracil depend on IFN-gamma.
    Int J Cancer 121: 878-883, 2007.
  8. Yamaguchi S, Tatsumi T, Takehara T, Sakamori R, Uemura A, Mizushima T, Ohkawa K, Storkus WJ, Hayashi N.
    Immunotherapy of murine colon cancer using receptor tyrosine kinase EphA2-derived peptide-pulsed dendritic cell vaccines.
    Cancer 110: 1469-1477, 2007.
  9. Sakamori R, Takehara T, Ohnishi C, Tatsumi T, Ohkawa K, Takeda K, Akira S, Hayashi N.
    Signal transducer and activator of transcription 3 signaling within hepatocytes attenuates systemic inflammatory response and lethality in septic mice.
    Hepatology 46: 1564-1573, 2007.
  10. Kanada A, Takehara T, Ohkawa K, Tatsumi T, Sakamori R, Yamaguchi S, Uemura A, Kohga K, Sasakawa A, Hikita H, Hijioka T, Katayama K, Deguchi M, Kagita M, Kanto T, Hiramatsu N, Hayashi N.
    Type B Fulminant Hepatitis Is Closely Associated with a Highly Mutated Hepatitis B Virus Strain.
    Intervirology 50: 3 49-401, 2007.
  11. Nishida T, Yabe Y, Fu,Hayashi Y, Asahi K, Eguchi H, Tsuji S ,Tsujii M., Hayashi N, Kawano S.
    Geranylgeranylacetone Induces Cyclooxygenase-2 Expression In Cultured Rat Gastric Epithelial Cells through NF-κB.
    Dig Dis Sci, 52: 1890-1896,2007
  12. Kamada Y, Matsumoto H, Tamura S, Fukushima J, Kiso S, Fukui K, Igura T, Maeda N, Kihara S, Funahashi T, Matsuzawa Y, Shimomura I, Hayashi N.
    Hypoadiponectinemia accelerates hepatic tumor formation in a nonalcoholic steatohepatitis mouse model.
    J Hepatol. 47: 556-564, 2007.
  13. Moriwaki K, Noda K, Nakagawa T, Asahi M, Yoshihara H, Taniguchi N, Hayashi N and Miyoshi E.
    A high expression of GDP-fucose transporter in hepatocellular carcinoma is a key factor for increases in fucosylation.
    Glycobiology 17:1311-1320,2007.
  14. Doi Y Tamura S, Nammo T, Fukui K, Kiso S, and Nagafuchi A
    Development of complementary expression patterns of E-and N-cadherin in the mouse liver.
    Hepatology Research 37:230-237 2007.