阪大消化器内科のご紹介・研究実績



2017年

原著論文

  1. Shinzaki S, Matsuoka K, Iijima H, Mizuno S, Serada S, Fujimoto M, Arai N, Koyama N, Morii E, Watanabe M, Hibi T, Kanai T, Takehara T, Naka T.
    Leucine-rich alpha-2 glycoprotein is a serum biomarker of mucosal healing in ulcerative colitis.
    J Crohns Colitis. 2017 Jan;11(1):84-91.
  2. Nishio A, Tatsumi T, Nawa T, Suda T, Yoshioka T, Onishi Y, Aono S, Shigekawa M, Hikita H, Sakamori R, Okuzaki D, Fukuhara T, Matsuura Y, Hiramatsu N, Takehara T.
    CD14+ monocyte-derived Galectin-9 induces NK cell cytotoxicity in chronic hepatitis C.
    Hepatology. 2017 Jan;65(1):18-31.
  3. Kai Y, Hikita H, Morishita N, Murai K, Nakabori T, Iio S, Hagiwara H, Imai Y, Tamura S, Tsutsui S, Naito M, Nishiuchi M, Kondo Y, Kato T, Suemizu H, Yamada R, Oze T, Yakushijin T, Hiramatsu N, Sakamori R, Tatsumi T, Takehara T.
    Baseline quasispecies selection and novel mutations contribute to emerging resistance-associated substitutions in hepatitis C virus after direct-acting antiviral treatment.
    Sci Rep. 2017 Jan 30;7:41660.
  4. Yoshii S, Hayashi Y, Tsujii Y, Takehara T.
    Underwater endoscopic submucosal dissection: a novel resection strategy for early gastric cancer located on the greater curvature of the gastric body.
    Ann Gastroenterol. 2017 Jan;30(3):364.
  5. Tsujii Y, Hayashi Y, Maekawa A, Fujinaga T, Nagai K, Yoshii S, Sakatani A, Hiyama S, Shinzaki S, Iijima H, Takehara T.
    Cardiac metastasis from colon cancer effectively treated with 5-fluorouracil, leucovorin, and oxaliplatin (modified FOLFOX6) plus panitumumab: a case report.
    BMC Cancer. 2017 Feb 23;17(1):152.
  6. Ikezawa K, Hikita H, Shigekawa M, Iwahashi K, Eguchi H, Sakamori R, Tatsumi T, Takehara T.
    Increased Bcl-xL Expression in Pancreatic Neoplasia Promotes Carcinogenesis by Inhibiting Senescence and Apoptosis.
    Cell Mol Gastroenterol Hepatol. 2017 Feb 20;4(1):185-200.
  7. Yoshii S, Hayashi Y, Takehara T.
    Helicobacter pylori-negative early gastric adenocarcinoma with complete intestinal mucus phenotype mimicking verrucous gastritis.
    Dig Endosc. 2017 Mar;29(2):235-236.
  8. Yoshioka T, Tatsumi T, Miyagi T, Mukai K, Nishio K, Nishio A, Yokoyama Y, Suda T, Kegasawa T, Shigekawa M, Hikita H, Sakamori R, Takehara T.
    Frequency and role of NKp46 and NKG2A in hepatitis B virus infection.
    PLoS One. 2017 Mar 22;12(3):e0174103.
  9. Shinzaki S, Iijima H, Fujii H, Kamada Y, Naka T, Takehara T, Miyoshi E.
    A novel pathogenesis of inflammatory bowel disease from the perspective of glyco-immunology.
    J Biochem. 2017 May 1;161(5):409-415.
  10. Morishita N, Hiramatsu N, Oze T, Urabe A, Tahata Y, Yamada R, Yakushijin T, Hosui A, Iio S, Yamada A, Hagiwara H, Mita E, Yamada Y, Ito T, Inada M, Katayama K, Yabuuchi I, Imai Y, Hikita H, Sakamori R, Yoshida Y, Tatsumi T, Hayashi N, Takehara T.
    Ultra-deep sequencing analysis of resistance-associated variants during retreatment with simeprevir-based triple therapy after failure of telaprevir-based triple therapy in patients with genotype 1 hepatitis C virus infection.
    Hepatol Res. 2017 Jul;47(8):773-782.
  11. Tsujii Y, Hayashi Y, Kawai N, Yamada T, Yamamoto K, Hayashi S, Yoshii S, Nagai K, Inoue T, Nishida T, Iijima H, Mita E, Inoue A, Takehara T.
    Risk of perforation in balloon dilation associated with steroid injection for preventing esophageal stricture after endoscopic submucosal dissection.
    Endosc Int Open. 2017 Jul;5(7):E573-E579.
  12. Hosui A, Tatsumi T, Hikita H, Saito Y, Hiramatsu N, Tsujii M, Hennighausen L, Takehara T.
    STAT5 plays a crucial role in hepatic lipid metabolism through regulation of CD36 expression.
    Hepatol Res. 2017 Jul;47(8):813-825.
  13. Kawai S, Iijima H, Shinzaki S, Hiyama S, Yamaguchi T, Araki M, Iwatani S, Shiraishi E, Mukai A, Inoue T, Hayashi Y, Tsujii M, Motooka D, Nakamura S, Iida T, Takehara T.
    Indigo Naturalis ameliorates murine dextran sodium sulfate-induced colitis via aryl hydrocarbon receptor activation.
    J Gastroenterol. 2017 Aug;52(8):904-919.
  14. Egawa M, Yoshida Y, Ogura S, Kurahashi T, Kizu T, Furuta K, Kamada Y, Chatani N, Hamano M, Kiso S, Hikita H, Tatsumi T, Eguchi H, Nagano H, Doki Y, Mori M, Takehara T.
    Increased expression of Forkhead box M1 transcription factor is associated with clinicopathological features and confers a poor prognosis in human hepatocellular carcinoma.
    Hepatol Res. 2017 Oct;47(11):1196-1205.
  15. Kamada Y, Maekawa T, Ebisutani Y, Yamamoto A, Takamatsu S, Takehara T, Miyoshi E.
    Use of Mac-2 binding protein as a biomarker for nonalcoholic fatty liver disease diagnosis.
    Hepatol Commun. 2017 Oct;1(8):780-791.
  16. Araki M, Shinzaki S, Yamada T, Arimitsu S, Komori M, Shibukawa N, Mukai A, Nakajima S, Kinoshita K, Kitamura S, Murayama Y, Ogawa H, Yasunaga Y, Oshita M, Fukui H, Masuda E, Tsujii M, Hiyama S, Inoue T, Iijima H, Takehara T.
    Age at onset is associated with the seasonal pattern of onset and exacerbation in inflammatory bowel disease.
    J Gastroenterol. 2017 Nov;52(11):1149-1157.
  17. Yoshihara T, Shinzaki S, Kawai S, Fujii H, Iwatani S, Yamaguchi T, Araki M, Hiyama S, Inoue T, Hayashi Y, Watabe K, Iijima H, Takehara T.
    Tissue Drug Concentrations of Anti-tumor Necrosis Factor Agents Are Associated with the Long-term Outcome of Patients with Crohn's Disease.
    Inflamm Bowel Dis. 2017 Dec;23(12):2172-2179.
  18. Doi A, Sakamori R, Tahata Y, Urabe A, Morishita N, Yamada R, Furuta K, Kodama T, Hikita H, Yakushijin T, Ohkawa K, Kaneko A, Imai Y, Tatsumi T, Takehara T.
    Frequency of, and factors associated with, hepatitis B virus reactivation in hepatitis C patients treated with all-oral direct-acting antivirals: Analysis of a Japanese prospective cohort.
    Hepatol Res. 2017 Dec;47(13):1438-1444.

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