阪大消化器内科のご紹介・研究実績
2010年
- Yamaguchi S, Tatsumi T, Takehara T, Sasakawa A, Yamamoto M, Kohga K, Miyagi T, Kanto T, Hiramastu N, Akagi T, Akashi M, Hayashi N.
EphA2-derived peptide vaccine with amphiphilic poly(gamma-glutamic acid) nanoparticles elicits an anti-tumor effect against mouse liver tumor.
Cancer Immunol Immunother 59:759-767, 2010 - Kohga K, Takehara T, Tatsumi T, Ishida H, Miyagi T, Hosui A, Hayashi N.
Sorafenib inhibits the shedding of major histocompatibility complex class I-related chain A on hepatocellular carcinoma cells by down-regulating a disintegrin and metalloproteinase 9.
Hepatology 51: 1264-1273, 2010 - Ohkawa K, Takehara T, Tatsumi T, Ishida H, Deguchi M, Kagita M, Hosui A, Miyagi T, Katayama K, Hayashi N.
Alterations in hepatitis B virus nucleotide sequences in a chronic virus carrier from immunotolerant to immunoactive phase.
Biochem Biophys Res Commun 394: 574-580, 2010 - Ohkawa K, Takehara T, Ishida H, Kodama T, Shimizu S, Hikita H, Yamamoto M, Kohga K, Sasakawa A, Uemura A, Sakamori R, Yamaguchi S, Li W, Hosui A, Miyagi T, Tatsumi T, Katayama K, Hayashi N.
Fatal exacerbation of type B chronic hepatitis triggered by changes in relaxed circular viral DNA synthesis and virion secretion.
Biochem Biophys Res Commun 394: 87-93, 2010 - Sakamori R, Takehara T, Tatsumi T, Shigekawa M, Hikita H, Hiramatsu N, Kanto T, Hayashi N.
STAT3 signaling within hepatocytes is required for anemia of inflammation in vivo.
J Gastroenterol 45: 244-248, 2010 - Imai Y, Tamura S, Tanaka H, Hiramatsu N, Kiso S, Doi Y, Inada M, Nagase T, Kitada T, Imanaka K, Fukuda K, Takehara T, Kasaha A, Hayashi N.
Reduced risk of hepatocellular carcinoma after intetferon therapy in aged patients with chronic hepatitis C is limited to sustained virological responders.
J Viral Hepat 17:185-191, 2010 - Yamada T, Araki H, Watabe K, Kamada Y, Kiso S, Ogiyama H, Nishihara T, Kihara S, Funahashi T, Shimomura I, Tsutsui S, Hayashi N.
Adiponectin deficiency enhanced the severity of cerulein-induced chronic pancreatitis in mice.
J Gastroenterol 45(7):742-9,2010 - Kodama T, Takehara T, Hikita H, Shimizu S, Li W, Miyagi T, Hosui A, Tatsumi T, Ishida H, Tadokoro S, Ido A, Tsubouchi H, Hayashi N.
Thrombocytopenia exacerbates cholestasis-induced liver fibrosis in mice.
Gastroenterology Jun;138(7):2487-98,2010 - Kondo J, Iijima H, Abe T, Komori M, Hiyama S, Ito T, Nakama A, Tominaga K, Kubo M, Suzuki K, Iwanaga Y, Ebara R, Takeda A, Tsuji S, Nishida T, Tsutsui S, Tsujii M, Hayashi N.
Roles of double-balloon endoscopy in the diagnosis and treatment of Crohn's disease: a multicenter experience.
J Gastroenterol 45(7):713-20 , 2010 - Yamamoto S, Tsutsui S, Hayashi N.
Esophageal Intramural Pseudodiverticulosis: A Rare Cause of Esophageal Stricture.
Clin Gastroenterol Hepatol 8(7):A28,2010 - Shimizu S, Takehara T, Hikita H, Kodama T, Miyagi T, Hosui A, Tatsumi T, Ishida H, Noda T, Nagano H, Doki Y, Mori M, Hayashi N.
The let-7 family of microRNAs inhibits Bcl-xL expression and potentiates sorafenib-induced apoptosis in human hepatocellular carcinoma.
J Hepatol ;52(5):698-704,2010 - Kohga K, Tatsumi T, Takehara T, Tsunematsu H, Yamamoto M, Sasakawa A, Shimizu S, Miyagi T, Hayashi N.
Expression of CD133 confers malignant potential by regulating metalloproteinase in human hepatocellular carcinoma.
J Hepatol ;52(6):872-9,2010 - Miyagi T, Takehara T, Nishio K, Shimizu S, Kohga K, Tatsumi T, Kanto T, Hiramatsu N, Hayashi N.
Altered impaired interferon-alfa-signaling in NK cells from the patients with chronic hepatitis C virus infection.
J Hepatol 53(3):424-30 , 2010 - Oze T, Hiramatsu N, Yakushijin T, Mochizuki K, Oshita M, Hagiwara H, Mita E, Ito T, Fukui H, Inui Y, Hijioka T, Inada M, Kaytayama K, Tamura S, Yoshihara H, Inoue A, Imai Y, Kato M, Miyagi T,Yoshida Y, Tatsumi T, Kiso S, Kanto T, Kasahara A, Takehara T, Hayashi N.
Indications and limitations for aged patients with chronic hepatitis C in pegylated interferon alfa-2b plus ribavirin combination therapy.
J Hepatol. 2011 Apr;54(4):604-11 - Tatsumi T, Takehara T, Miyagi T, Sugiyama T, Aketa H, Sasakawa A, Kanto T, Hiramatsu N, Hayashi N.
α-Galactosylceramide activates antitumor immunity against liver tumor.
Hepatol Res. 2011 Feb;41(2):160-9. - Tatsumi T, Takehara T, Miyagi T, Nakazuru S, Mita E, Kanto T, Hiramatsu N, Hayashi N.
Hepatitis C virus-specific CD8+ T cell frequencies are associated with the responses of pegylated interferon-α and ribavirin combination therapy in patients with chronic hepatitis C virus infection.
Hepatol Res. 2011 Jan;41(1):30-8. - Hikita H, Takehara T, Shimizu S, Kodama T, Shigekawa M, Iwase K, Hosui A, Miyagi T, Tatsumi T, Ishida H, Li W, Kanto T, Hiramatsu N, Hayashi N.
The Bcl-xL inhibitor, ABT-737, efficiently induces apoptosis and suppresses growth of hepatoma cells in combination with sorafenib.
Hepatology. 2010 Oct;52(4):1310-21. - Ogiyama H, Kamada Y, Kiso S, Araki H, Yamada T, Nishihara T, Watabe K, Tochino Y, Kihara S, Funahashi T, Kanno K, Shimomura I, Tsutsui S, Tazuma S, Hayashi N.
Lack of adiponectin promotes formation of cholesterol gallstones in mice.
Biochem Biophys Res Commun. 2010 Aug 27;399(3):352-8 - Miyagi T, Takehara T, Uemura A, Nishio K, Shimizu S, Kodama T, Hikita H, Li W, Sasakawa A, Tatsumi T, Ohkawa K, Kanto T, Hiramatsu N, Hayashi N
Absence of invariant natural killer T cells deteriorates liver inflammation and fibrosis in mice fed high-fat diet.
J Gastroenterol. 45(12):1247-54,2010 - Nishida T, Tsutsui S, Yamamoto K, Konishi K, Hayashi Y, Iijima H, Tsujii M, Takeda Y, Kitagawa T, Yoshioka Y, Inoue T, Hayashi N.
Phase I trial of gemcitabine dose escalation with concurrent radiotherapy for patients with locally advanced pancreatic cancer.
Pancreatology. 2010;10(1):60-5 - Kondo J, Iijima H, Abe T, Komori M, Hiyama S, Ito T, Nakama A, Tominaga K, Kubo M, Suzuki K, Iwanaga Y, Ebara R, Takeda A, Tsuji S, Nishida T, Tsutsui S, Tsujii M, Hayashi N.
Roles of double-balloon endoscopy in the diagnosis and treatment of Crohn's disease: a multicenter experience.
J Gastroenterol. 2010 Jul;45(7):713-20
