RESULTS

In collaboration with Osaka University (Profs Yuichiro Doki and Masaki Mori, and Associate Prof Hidetoshi Eguchi), Konno et al. have studied the methylation events in miRNA by utilizing the MS-based new technology and have found that the epitranscriptome information is critical for the accurate diagnosis of gastrointestinal cancers, suggesting that the findings provide a basis for new diagnostic strategies for early stage cancer and add a new dimension to our understanding of miRNA biology.