CD44/CD133-positive colorectal cancer stem cells are sensitive to trifluridine (FTD) exposure (Scientific Reports, 2019, in press).

CD44/CD133-positive colorectal cancer stem cells are sensitive to trifluridine (FTD) exposure (Scientific Reports, 2019, in press).
In collaboration with Taiho Pharmaceutical Co., Ltd, as well as Osaka University (Profs Yuichiro Doki and Masaki Mori), Tsunekuni et al. studied the effects of FTD exposure to CD44/CD133-positive cancer stem cells (CSCs) and elucidated firstly the mechanism on CSC-targeting FTD-containing chemotherapy for colorectal cancer.