RESULTS

Cancer stem cells: the potential of carbon ion beam radiation and new radiosensitizers (Review) （Oncology Rep., 2015 ）

In  the collaboration with the Department of Radiation Oncology, Osaka University (Prof. Ogawa, K.), Baek , et al. update the information regarding  carbon ion beam radiation and new radio sensitizers. Given that cancer stem cells (CSCs) are a small population of cells in cancer with stem-like properties such as cell proliferation, and CSCs are therapy-resistant and cause cancer metastasis and recurrence, one key issue in cancer therapy may be the carbon ion beam radiotherapy, being a promising treatment for CSCs. Evidence indicates that the carbon ion beam is more effective against CSCs than the conventional X-ray beam. Combination therapies of radiosensitizing microRNAs and carbon ion beam radiotherapy may be a promising cancer strategy.