RESULTS

Embryonic microRNA-369 controls metabolic splicing factors and urges cellular reprograming (PLOS ONE, 2015)

In collaboration with the Department of Surgery, Osaka University (Profs. Masaki Mori and Yuichiro Doki), Konno et al. found a unique role of the embryonic miR-369- HNRNPA2B1  axis in controlling metabolic enzyme function. The data suggest a novel pathway linking epigenetic, transcriptional, and metabolic control in cell reprogramming, and may be useful for the novel diagnostic approaches and therapies in regenerative medicine and cancer research.