英文論文
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題名 | 著者 | 誌名 & DOI | ||
2024 | 1 | eIF5 stimulates the CUG initiation of RAN translation of poly-GA dipeptide repeat protein (DPR) in C9orf72 FTLD/ALS | Shiho Gotoh, Kohji Mori, Yuzo Fujino, Yuya Kawabe, Tomoko Yamashita, Tsubasa Omi, Kenichi Nagata, Shinji Tagami, Yoshitaka Nagai, Manabu Ikeda | Journal of Biological Chemistry 300.3 (2024). DOI: 10.1016/j.jbc.2024.105703 |
2 | PABPC1 mediates degradation of C9orf72-FTLD/ALS GGGGCC repeat RNA | Ryota Uozumi, Kohji Mori, Shiho Gotoh, Tesshin Miyamoto, Shizuko Kondo, Tomoko Yamashita, Yuya Kawabe, Shinji Tagami, Shoshin Akamine, Manabu Ikeda | iScience (2024). DOI: 10.1016/j.isci.2024.109303 | |
3 | Gene-gene functional relationships in Alzheimer's disease: CELF1 regulates KLC1 alternative splicing | Masataka Kikuchi, Justine Viet, Kenichi Nagata, Masahiro Sato, Geraldine David, Audic Yann, Michael A. Silverman, Mitsuko Yamamoto, Hiroyasu Akatsu, Yoshio Hashizume, Shuko Takeda, Shoshin Akamine, Tesshin Miyamoto, Ryota Uozumi, Shiho Gotoh, Kohji Mori, Manabu Ikeda, Luc Paillard, Takashi Morihara | Biochemical and Biophysical Research Communications (2024). DOI: 10.1016/j.bbrc.2024.150025 | |
4 | Utilizing portable electroencephalography to screen for pathology of Alzheimer's disease: a methodological advancement in diagnosis of neurodegenerative diseases | Masahiro Hata, Yuki Miyazaki, Kohji Mori, Kenji Yoshiyama, Shoshin Akamine, Hideki Kanemoto, Shiho Gotoh, Hisaki Omori, Atsuya Hirashima, Yuto Satake, Takashi Suehiro, Shun Takahashi, Manabu Ikeda | Frontiers in Psychiatry (2024). DOI: 10.3389/fpsyt.2024.1392158 | |
5 | Protocols for identifying endogenous interactors of RNA-binding proteins in mammalian cells using the peroxidase APEX2 biotin-labeling method | Ryota Uozumi, Kohji Mori, Shoshin Akamine, Manabu Ikeda | STAR Protocols (2024). DOI: 10.1016/j.xpro.2024.103368 | |
2023 | 1 | RNA Dysmetabolism and Repeat-Associated Non-AUG Translation in Frontotemporal Lobar Degeneration/Amyotrophic Lateral Sclerosis due to C9orf72 Hexanucleotide Repeat Expansion | Kohji Mori, Shiho Gotoh, Ryota Uozumi, Tesshin Miyamoto, Shoshin Akamine, Yuya Kawabe, Shinji Tagami, and Manabu Ikeda. | JMA journal, 6(1) 9-15. DOI: 10.31662/jmaj.2022-0160. |
2 | Characteristics of very late-onset schizophrenia-like psychosis classified with the biomarkers for Alzheimer's disease: a retrospective cross-sectional study | Yuto Satake, Hideki Kanemoto, Daiki Taomoto, Takashi Suehiro, Fuyuki Koizumi, Shunsuke Sato, Tamiki Wada, Keiko Matsunaga, Eku Shimosegawa, Shiho Gotoh, Kohji Mori, Takashi Morihara, Kenji Yoshiyama, Manabu Ikeda | International Psychogeriatrics, Volume 36, Issue 1, 2024, Pages 64-77. DOI: https://doi.org/10.1017/s1041610222001132 | |
3 | Repeat-associated non-AUG translation in neuromuscular diseases: mechanisms and therapeutic insights | Yuzo Fujino, Kohji Mori, Yoshitaka Nagai | The Journal of Biochemistry. DOI: 10.1093/jb/mvad012 | |
4 | Aspects of degradation and translation of the expanded C9orf72 hexanucleotide repeat RNA | Kohji Mori, Shiho Gotoh, Manabu Ikeda | Journal of Neurochemistry. DOI: 10.1111/jnc.15847 | |
5 | A heterozygous splicing variant IVS9-7A > T in intron 9 of the MAPT gene in a patient with right-temporal variant frontotemporal dementia with atypical 4 repeat tauopathy | Kohji Mori, Kazue Shigenobu, Goichi Beck, Ryota Uozumi, Yuto Satake, Maki Suzuki, Shizuko Kondo, Shiho Gotoh, Yuki Yonenobu, Makiko Kawai, Yuki Suzuki, Yuko Saito, Eiichi Morii, Masato Hasegawa, Hideki Mochizuki, Shigeo Murayama & Manabu Ikeda | Acta Neuropathologica Communications 11.1 (2023): 130. DOI: 10.1186/s40478-023-01629-3 | |
6 | Cerebrospinal fluid amyloid beta with amyloid positron emission tomography concordance rates in a heterogeneous group of patients including late‐onset psychotic disorders: a retrospective cross‐sectional study | Yuto Satake, Hideki Kanemoto, Shiho Gotoh, Shoshin Akamine, Takashi Suehiro, Keiko Matsunaga, Eku Shimosegawa, Kenji Yoshiyama, Takashi Morihara, Kohji Mori, Manabu Ikeda | Psychogeriatrics 23.6 (2023). DOI: 10.1111/psyg.13024 | |
2022 | 1 | Therapeutic reduction of GGGGCC repeat RNA levels by hnRNPA3 suppresses neurodegeneration in Drosophila models of C9orf72-linked ALS/FTD | Tomoya Taminato, Toshihide Takeuchi*, Morio Ueyama, Kohji Mori, Manabu Ikeda, Hideki Mochizuki, Yoshitaka Nagai* | Human Molecular Genetics |
2 | Drug screen in iPSC-Neurons identifies nucleoside analogs as inhibitors of (G4C2)n expression in C9orf72 | Czuppa M, Dhingra A, Zhou Q, Schludi C, König L, Scharf E, Farny D, Dalmia A, Täger J, Castillo-Lizardo M, Katona E, Mori K, Aumer T, Schelter F, Müller M, Carell T, Kalliokoski T, Messinger J, Rizzu P, Heutink P, Edbauer D. | Cell Reports 39, 110913, June 7, 2022 | |
3 | An Alzheimer's disease pathway uncovered by functional omics: the risk gene CELF1 regulates KLC1 | Kikuchi M, Viet J, Nagata K, Sato M, David G, Audic Y, Silverman MA, Yamamoto M, Akatsu H, Hashizume Y, Chiba K, Takeda S, Akamine S, Miyamoto T, Uozumi R, Gotoh S, Mori K, Ikeda M, Paillard L, Morihara T. | MedRxiv, Posted March 02, 2022. | |
4 | FUS regulates RAN translation through modulating the G-quadruplex structure of GGGGCC repeat RNA | Fujino Y, Ueyama M, Ishiguro T, Ozawa D, Sugiki T, Ito H, Murata A, Ishiguro A, Gendron TF, Mori K | BioRxiv Posted November 01, 2022. | |
5 | RNA dysmetabolism and repeat associated non-AUG translation in Frontotemporal Lobar | Mori K*, Gotoh S, Uozumi R, Miyamoto T, Akamine S, Kawabe Y, Tagami S, Ikeda M | JMA Journal Vol. 6, No. 1, 2023 | |
6 | Biological basis and psychiatric symptoms in frontotemporal dementia | Mori K*, Ikeda M | Psychiatry and Clinical Neuroscience, 76, 351-360, 2022 | |
2021 | 1 | The porphyrin TMPyP4 inhibits elongation during the noncanonical translation of the FTLD/ALS-associated GGGGCC repeat in the C9orf72 gene | Mori K, Gotoh S, Yamashita T, Uozumi R, Kawabe Y, Tagami S, Kamp F, Nuscher B, Edbauer D, Haass C, Nagai Y, Ikeda M. | J Biol Chem Oct; 297(4):101120, 2021 [Published online 25 Aug 2021] |
2 | Repurposing bromocriptine for Aβ metabolism in Alzheimer's disease (REBRAnD) study: Randomised Placebo-Controlled Double-Blind Comparative Trial and Open-Label Extension Trial to Investigate the Safety and Efficacy of Bromocriptine in Alzheimer's Disease with Presenilin 1 (PSEN1) Mutations | Kondo T, Banno H, Okunomiya T, Amino Y, Endo K, Nakakura A, Uozumi R, Kinoshita A, Tada H, Morita S, Ishikawa H, Shindo A, Yasuda K, Taruno Y, Maki T, Suehiro T, Mori K, Ikeda M, Fujita K, Izumi Y, Kanemaru K, Ishii K, Shigenobu K, Kutoku Y, Sunada Y, Kawakatsu S, Shiota S, Watanabe T, Uchikawa O, Takahashi R, Tomimoto H, Inoue H | BMJ Open 11(6) e051443, 2021 |
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2020 | 1 | Successive cleavage of β-amyloid precursor protein by γ-secretase | Funamoto S, Tagami S, Okochi M, Morishima-Kawashima M. | Seminars in Cell and Developmental Biology, Sep;105:64-74. 2020 doi: 10.1016/j.semcdb. 2020.04.002. |
2 | Clinical trials for Alzheimer disease and perspectives | Tagami S, Takeda M, Okochi M. | Cognition & Rehabilitation. Dec;p12-19 Vol.1 2020 |
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3 | Poly-Glycine-Alanine exacerbates C9orf72 repeat expansion-mediated DNA damage via sequestration of phosphorylated ATM and loss of nuclear hnRNPA3 | Nihei Y, Mori K, Werner G, Arzberger T, Zhou Q, Khosravi B, Japtok J, Hermann A, Sommacal A, Weber M, German Consortium for Frontotemporal Lobar Degeneration, Bavarian Brain Banking Alliance, Kamp F, Nuscher B, Edbauer D, Haass C. | Acta Neuropathologica 139(1), 99-118, 2020 |
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4 | A History of Antidementic Drug Development in Japan | Takeda M, Tagami S. | Taiwan J of Psychiatry, 34 p152-161, 2020 |
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2019 | 1 | Efficacy, Safety, and Tolerability of Switching from Oral Cholinesterase Inhibitors to Rivastigmine Transdermal Patch with 1-Step Titration in Patients with Mild to Moderate Alzheimer's Disease: A 24-Week, Open-Label, Multicenter Study in Japan. | Ueda K, Katayama S, Arai T, Furuta N, Ikebe S, Ishida Y, Kanaya K, Ouma S, Sakurai H, Sugitani M, Takahashi M, Tanaka T, Tsuno N, Wakutani Y, Shekhawat A, Das Gupta A, Kiyose K, Toriyama K, Nakamura Y. | Dement Geriatr Cogn Dis Extra. 15;9(2):302-318、 2019 doi: 10.1159/000501364. eCollection 2019 May-Aug. |
2 | Cerebral blood flow and Alzheimer's disease-related biomarkers in cerebrospinal fluid in idiopathic normal pressure hydrocephalus. | Azuma S, Kazui H, Kanemoto H, Suzuki Y, Sato S, Suehiro T, Matsumoto T, Yoshiyama K, Kishima H, Shimosegawa E, Tanaka T, Ikeda M. | Psychogeriatrics. 19(6):527-538、 2019. doi: 10.1111/psyg. 12435. |
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3 | Apathy and right caudate perfusion in idiopathic normal pressure hydrocephalus: a case-control study. | Kanemoto H, Kazui H, Suehiro T, Kishima H, Suzuki Y, Sato S, Azuma S, Matsumoto T, Yoshiyama K, Shimosegawa E, Tanaka T, Ikeda M. | Int J Geriatr Psychiatry. 34(3): 453-462、2019 doi:10.1002/ gps.5038. |
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2018 | 1 | Two neuropsychiatric cases seropositive for bornavirus improved by ribavirin | Matsunaga H, Fukumori A, Mori K, Honda T, Uema T, Tomonaga K | Japanese Journal of Infectious Diseases 71(5):338-342, 2018 |
2 | Making the final cut: pathogenic amyloid-β peptide generation by γ-secretase | Steiner H, Fukumori A, Tagami S, Okochi M | Cell Stress. 2018 in press |
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2017 | 1 | Neural Basis of Apathy in Patients with Amnestic Mild Cognitive Impairment. | Kazui H, Takahashi R, Yamamoto Y, Yoshiyama K, Kanemoto H, Suzuki Y, Sato S, Azuma S, Suehiro T, Shimosegawa E, Ishii K, Tanaka T. | J Alzheimers Dis.2017;55(4): 1403-1416. doi: 10.3233/ JAD-160223. |
2 | Effects of donepezil on sleep disturbances in patients with dementia with Lewy bodies: an open-label study with actigraphy. | Kazui H, Adachi H, Kanemoto H, Yoshiyama K, Wada T, Tokumasu-Nomura K, Tanaka T, Ikeda M. | Psychiat Res. doi: http://dx.doi.org/ 10.1016/ j.psychres. 2017.02.039 |
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3 | Semagacestat Is a Pseudo-Inhibitor of γ-Secretase. | Tagami S, Yanagida K, Kodama TS, Takami M, Mizuta N, Oyama H, Nishitomi K, Chiu YW, Okamoto T, Ikeuchi T, Sakaguchi G, Kudo T, Matsuura Y, Fukumori A, Takeda M, Ihara Y, Okochi M. | Cell Rep. 2017 Oct 3;21(1): 259-273. doi:10.1016/j.celrep. 2017.09.032. |
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4 | Heterogeneous ribonuclear protein A3 (hnRNP A3) is present in dipeptide repeat protein containing inclusions in Frontotemporal Lobar Degeneration and Motor Neurone disease associated with expansions in C9orf72 gene | Davidson YS, Flood L, Robinson AC, Nihei Y, Mori K, Rollinson S, Richardson A, Benson BC, Jones M, Snowden JS, Pickering-Brown S, Haass C, Lashley T, Mann DMA | Acta Neuropathologica Communications 5:31, 2017 |
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5 | Antibodies inhibit transmission and aggregation of C9orf72 poly-GA dipeptide repeat proteins | Zhou Q, Lehmer C, Michaelsen M, Mori K, Alterauge D, Baumjohann D, Schludi MH, Greiling J, Farny D, Flatley A, Feederle R, May S, Schreiber F, Arzberger T, Kuhm C, Klopstock T, Hermann A, Haass C, Edbauer D | EMBO Molecular Medicine 9(5): 687-702, 2017 |
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6 | Positive symptoms associate with cortical thinning in the superior temporal gyrus via the ENIGMA-Schizophrenia consortium. | Walton E, (24名中略)Hashimoto R (60名中25番目)(33名中略)Ehrlich S. | Acta Psychiatrica Scandinavica, 135(5):439-447, 2017 |
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7 | Transethnic replication study to assess the association between clozapine-induced agranulocytosis/granulocytopenia and genes at 12p12.2 in a Japanese population. | Saito T, Ikeda M, Hashimoto R, Clozapine Pharmacogenomics Consortium of Japan (CPC-J), Iwata N. | Biol Psychiatry, 82(1):e9-e10, 2017 |
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8 | Microglia-derived neuregulin expression in psychiatric disorders. | Ikawa D, Makinodan M, Iwata K, Ohgidani M, Kato T, Yamashita Y, Yamamuro K, Kimoto S, Toritsuka M, Yamauchi T, Fukami S, Yoshino H, Okumura K, Tanaka T, Wanaka A, Owada Y, Tsujii M, Sugiyama T, Tsuchiya K, Mori N, Hashimoto R, Matsuzaki H, Kanba S, Kishimoto T. | Brain Behav Immun, 61: 375-385, 2017 |
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9 | Human subcortical brain asymmetries in 15,847 people worldwide reveal effects of age and sex. | Guadalupe T, (62名中略) Hashimoto R,(160名中64番目)(95名中略)Francks C. | Brain Imaging and Behaviour 11(5): 1497-1514, 2017 |
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10 | A Brief Assessment of Intelligence Decline in Schizophrenia as Represented by the Difference between Current and Premorbid IQ. | Ohi K, Sumiyoshi C, Fujino H, Yasuda Y, Yamamori H, Fujimoto M, Sumiyoshi T, Hashimoto R. | Frontiers in Psyhiatry -Psyhopathology. 8:293, 2017 |
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11 | Effect of clozapine on DNA methylation in peripheral leukocytes frompatients with treatment-resistant schizophrenia. | Kinoshita M, Numata S, Tajima A, Yamamori H, Yasuda Y, Fujimoto M, Watanabe S, Umehara H, Shimodera S, Nakazawa T, Kikuchi M, Nakaya A, Hashimoto H, Imoto I, Hashimoto R, Ohmori T. | Int J Mol Sci, 18(3):632, 2017 |
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12 | High-resolution copy number variation analysis of schizophrenia in Japan. | Kushima I, Aleksic B, Nakatochi M, Shimamura T, Shiino T, Yoshimi A, Kimura H, Takasaki Y, Wang C, Xing J, Ishizuka K, Oya-Ito T, Nakamura Y, Arioka Y, Maeda T, Yamamoto M, Yoshida M, Noma H, Hamada S, Morikawa M, Uno Y, Okada T, Iidaka T, Iritani S, Yamamoto T, Miyashita M, Kobori A, Arai M, Itokawa M, Cheng MC, Chuang YA, Chen CH, Suzuki M, Takahashi T, Hashimoto R, Yamamori H, Yasuda Y, Watanabe Y, Nunokawa A, Someya T, Ikeda M, Toyota T, Yoshikawa T, Numata S, Ohmori T, Kunimoto S, Mori D, Iwata N, Ozaki N. | Mol Psychiatry, 22(3):430-440, 2017 |
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13 | Novel genetic loci associated with hippocampal volume. | Hibar DP, (199名中略) Hashimoto R,(332名中201番目)(130名中略)Ikram MA. | Nat Commun, 18;8:13624, 2017 |
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14 | ENIGMA and the individual : Predicting factors that affect the brain in 35 countries worldwide. | Thompson P, (29名中略)Hashimoto R, (71名中31番目)Wright M, Ye J, for the ENIGMA Consortium. | NeuroImage, 145 (Pt B):389-408, 2017 |
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15 | The effect of duration of illness and antipsychotics on subcortical volumes in schizophrenia: Analysis of 778 subjects. | Hashimoto N, Ito Y, Okada N, Yamamori H, Yasuda Y, Fujimoto M, Kudo N, Takemura A, Son S, Narita H, Yamamoto M, Tha KK, Katsuki A, Ohi K, Yamashita F, Koike S, Takahashi T, Nemoto K, Fukunaga M, Onitsuka T, Watanabe Y, Yamasue H, Suzuki M, Kasai K, Kusumi I, Hashimoto R, for COCORO. | NeuroImage Clin, 17;563-569, 2017 |
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16 | High-speed and scalable whole-brain imaging in rodents and primates. | Seiriki K, Kasai A, Hashimoto T, Schulze W, Niu M, Yamaguchi S, Nakazawa T, Inoue K, Uezono S, Takada M, Naka Y, Igarashi H, Tanuma M, Waschek JA, Ago Y, Tanaka KF, Hayata-Takano A, Nagayasu K, Shintani N, Hashimoto R, Kunii Y, Hino M, Matsumoto J, Yabe H, Nagai T, Fujita K, Matsuda T, Takuma K, Baba A, Hashimoto H. | Neuron, 94:1085-1100, 2017 |
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17 | Altered sulcogyral patterns of orbitofrontal cortex in a large cohort of patients with schizophrenia. | Isomura S, Hashimoto R, Nakamura M, Yamashita F, Jimbo S, Hirano Y, Yamamori H, Fujimoto M, Yasuda Y, Mears R, Onitsuka T. | NPJ Schizophrenia, 3(1):3:1-4, 2017 |
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18 | Cardiogenic shock caused by left mid-ventricular obstruction in a patient with anorexia nervosa; A novel cardiac manifestation of refeeding syndrome. | Sakamoto Y, Kioka H, Hashimoto R, Takeda S, Ohtani T, Yamaguchi O, Wasa M, Nakatani S, Sakata Y. | Nutrition, 35:148-150, 2017 |
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19 | Eye movement as a biomarker of schizophrenia:Using an integrated eye movement score | Morita K, Miura K, Fujimoto M, Yamamori H, Yasuda Y, Iwase M, Kasai K, Hashimoto R. | Psychiatry Clin Neurosci, 71(2): 104-114, 2017 |
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20 | Optimizing Outcomes in Clozapine Rechallenge Following Neutropenia Using Human Leukocyte Antigen Typing: A Case Report. | Yamaki N, Hishimoto A, Otsuka I, Sasada T, Boku S, Saito T, Yasuda Y, Yamamori H, Ikeda M, Ikeda M, Sora I, Iwata N, Hashimoto R. | Psychiatry Clin Neurosci, 71(4): 289-290, 2017 |
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21 | Estimated cognitive decline in patients with schizophrenia: a multi-center study. | Fujino H, Sumiyoshi C, Yasuda Y, Yamamori H, Fujimoto M, Fukunaga M, Miura K, Takebayashi Y, Okada N, Isomura S, Kawano N, Toyomaki A, Kuga H, Isobe M, Oya K, Okahisa Y, Takaki M, Hashimoto N, Kato M, Onitsuka T, Ueno T, Ohnuma T, Kasai K, Ozaki N, Sumiyoshi T, Imura O, Hashimoto R. | Psychiatry Clin Neurosci, 71(5): 294-300, 2017 |
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22 | Differential gene expression profiles in neurons generated from lymphoblastoid B-cell line-derived iPS cells from monozygotic twin cases with treatment-resistant schizophrenia and discordant responses to clozapine. | Nakazawa T, Kikuchi M, Ishikawa M, Yamamori H, Nagayasu K, Matsumoto T, Fujimoto M, Yasuda Y, Fujiwara M, Okada S, Matsumura K, Kasai A, Hayata-Takano A, Shintani N, Numata S, Takuma K, Akamatsu W, Okano H, Nakaya A, Hashimoto H, Hashimoto R. | Schizophr Res, 181:75-82, 2017 |
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2016 | 1 | Substrate Recruitment of γ-Secretase and Mechanism of Clinical Presenilin Mutations Revealed by Photoaffinity Mapping. | Fukumori A. and Steiner H | EMBO J. 35(15):1628-43, 2016 |
2 | Generation and deposition of Aβ43 by the virtually inactive presenilin-1 L435F mutant contradicts the presenilin loss-of-function hypothesis of Alzheimer's disease. | Kretner B, Trambauer J, Fukumori A, Mielke J, Kuhn PH, Kremmer E, Giese A, Lichtenthaler SF, Haass C, Arzberger T, Steiner H. | EMBO Mol Med. 8(5) 458-65, 2016 |
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3 | Substrate determinants of signal peptide peptidase-like 2a (SPPL2a)-mediated intramembrane proteolysis of the invariant chain CD74. | Hüttl S, Helfrich F, Mentrup T, Held S, Fukumori A, Steiner H, Saftig P, Fluhrer R, Schröder B. | Biochem J. 473(10):1405-22, 2016 |
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4 | Cleavage and cell adhesion properties of human epithelial cell adhesion molecule (HEPCAM). | Tsaktanis T, Kremling H, Pavšič M, von Stackelberg R, Mack B, Fukumori A, Steiner H, Vielmuth F, Spindler V, Huang Z, Jakubowski J, Stoecklein NH, Luxenburger E, Lauber K, Lenarčič B, Gires O. | J Biol Chem. 291(1):425, 2016 |
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5 | Proteolytic Processing of Neuregulin 1 Type III by Three Intramembrane-cleaving Proteases. | Fleck D, Voss M, Brankatschk B, Giudici C, Hampel H, Schwenk B, Edbauer D, Fukumori A, Steiner H, Kremmer E, Haug-Kröper M, Rossner MJ, Fluhrer R, Willem M, Haass C. | J Biol Chem. 291(1):318-33, 2016 |
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6 | Reduced hnRNPA3 increases C9orf72 repeat RNA levels and dipeptide-repeat protein deposition | Mori K, Nihei Y, Arzberger T, Zhou Q, Mackenzie I.R., Herrmann A, Hanisch F, German Consortium for Frontotemporal Lobar Degeneration, Bavarian Brain Banking Alliance, Kamp F, Nuscher B, Orozco D, Edbauer D, Haass C | EMBO Rep. 17(9):1314-25, 2016 |
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14 | Identification of Small Peptides in Human Cerebrospinal Fluid upon Amyloid-β Degradation | N.Mizuta, K.Yanagida, T.Kodama, T.Tomonaga, M.Takami, H.Oyama, T.Kudo, M.Ikeda, M.Takeda, S.Tagami, M.Okochi | Neurodegener Dis 2017;17: 103-109 |
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15 | Functional connectivity assessed by resting state EEG correlates with cognitive decline of Alzheimer's disease - An eLORETA study- | Hata M, Kazui H, Tanaka T, Ishii R, Leonides C, Pasqual-Marqui RD, Aoki Y, Ikeda S, Kanemooto H, Yoshiyama K, Iwase M,, Takeda M. | Clin Neurophysiol. 127(2): 1269-1278,2016 |
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16 | Sleep disturbances are key symptoms of very early stage Alzheimer disease with behavioral and psychological symptoms: a Japan multi-center cross-sectional study (J-BIRD). | Kabeshita Y, Adachi H, Matsushita M, Kanemoto H, Sato S, Suzuki Y, Yoshiyama K, Shimomura T, Yoshida T, Shimizu H, Matsumoto T, Mori T, Kashibayashi T, Tanaka H, Hatada Y, Hashimoto M, Nishio Y, Komori K, Tanaka T, Yokoyama K, Tanimukai S, Ikeda M, Takeda M, Mori E, Kudo T, Kazui H. | Int J Geriatr Psychiatry. 32(2): 222-230,2016. |
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17 | Cerebrospinal fluid biomarkers of Alzheimer's disease correlate with electroencephalography parameters assessed by exact Low-Resolution Electromagnetic Tomography (eLORETA). | Hata M, Tanaka T, Kazui H, Ishii R, Canuet L, Pascual-Marqui RD, Aoki Y, Ikeda S, Sato S, Suzuki Y, Kanemoto H, Yoshiyama K, Iwase M. | Clin EEG Neurosci. 2016 Aug 11. pii: 1550059416662119. |
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18 | Association between high biomarker probability of Alzheimer's disease and improvement of clinical outcomes after shunt surgery in patients with idiopathic normal pressure hydrocephalus. | Kazui H, Kanemoto H, Yoshiyama K, Kishima H, Suzuki Y, Sato S, Suehiro T, Azuma S1), Yoshimine T, Tanaka T. | J Neurol Sci. 369:236-241, 2016. |
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19 | Differences of Behavioral and Psychological Symptoms of Dementia in Disease Severity in Four Major Dementias. | Kazui H, Yoshiyama K, Kanemoto H, Suzuki Y, Sato S, Hashimoto M, Ikeda M, Tanaka H, Hatada Y, Matsushita M, Nishio Y, Mori E, Tanimukai S, Komori K, Yoshida T, Shimizu H, Matsumoto T, Mori T, Kashibayashi T, Yokoyama K, Shimomura T, Kabeshita Y, Adachi H, Tanaka T. | PLoS One. 11(8):e0161092, 2016 |
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2015 | 1 | Association of CSF tap-related oscillatory activity and shunt outcome in idiopathic normal pressure hydrocephalus. | Ikeda S, Kazui H, Tanaka T, Ishii R, Aoki Y, Hata M, Canuet L, Yoshiyama K, Iwase M, Takeda M. | Psychogeriatrics. 15(3):191-197, 2015. |
2 | Noninvasive prediction of shunt operation outcome in idiopathic normal pressure hydrocephalus. | Aoki Y, Kazui H, Tanaka T, Ishii R, Wada T, Ikeda S, Hata M, Canuet L, Katsimichas T, Musha T, Matsuzaki H, Imajo K, Yoshida T, Nomura K, Yoshiyama K, Iwase M, Takeda M. | Sci Rep. 5:7775. doi: 10.1038/srep07775. 2015. |
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3 | Resting-state synchrony between the retrosplenial cortex and anterior medial cortical structures relates to memory complaints in subjective cognitive impairment. | Yasuno F, Kazui H, Yamamoto A, Morita N, Kajimoto K, Ihara M, Taguchi A, Matsuoka K, Kosaka J, Tanaka T, Kudo T, Takeda M, Nagatsuka K, Iida H, Kishimoto T. | Neurobiol Aging. 36(6): 2145-52, 2015. |
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4 | Delayed atrophy in posterior cingulate cortex and apathy after stroke. | Matsuoka K, Yasuno F, Taguchi A, Yamamoto A, Kajimoto K, Kazui H, Kudo T, Sekiyama A, Kitamura S, Kiuchi K, Kosaka J, Kishimoto T, Iida H, Nagatsuka K | Int J Geriatr Psychiatry 30: 566-572, 2015 |
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5 | Fluvoxamine alleviates paclitaxel-induced neurotoxicity. | Tanimukai H, Kudo T | Biochem Biophys Reports 4, 202-206, 2015 |
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2014 | 1 | Fluvoxamine alleviates ER stress via induction of Sigma-1 receptor | Omi T, Tanimukai H, Kanayama D, Sakagami Y, Tagami S, Okochi M, Morihara T, Sato M, Yanagida K, Kitasyoji A, Hara H, Imaizumi K, Maurice T, Chevallier N, Marcha S, Takeda M, Kudo T | Cell Death and Disease 5, e1332, 2014 |
2 | In vitro acetylcholinesterase inhibitory activity and the antioxidant properties of Aegle marmelos leaf extract: implications for the treatment of Alzheimer's disease. | Asaduzzaman M, Uddin MJ, Kader MA, Alam AH, Rahman AA, Rashid M, Kato K, Tanaka T, Takeda M, Sadik G. | Psychogeriatrics. 14(1):1-10, 2014. |
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3 | Absolute Quantitation of Low Abundance Plasma APL1β peptides at Sub-fmol/mL Level by SRM/MRM without Immunoaffinity Enrichment. |
Sano S, Tagami S, Hashimoto Y, Yoshizawa-Kumagaye K, Tsunemi M, Okochi M, Tomonaga T. | J Proteome Res. 13(2):1012-20, 2014 |
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4 | Lack of genetic association between TREM2 and late-onset Alzheimer's disease in a Japanese population. | Miyashita A, Wen Y, Kitamura N, Matsubara E, Kawarabayashi T, Shoji M, Tomita N, Furukawa K, Arai H, Asada T, Harigaya Y, Ikeda M, Amari M, Hanyu H, Higuchi S, Nishizawa M, Suga M, Kawase Y, Akatsu H, Imagawa M, Hamaguchi T, Yamada M, Morihara T, Takeda M, Takao T, Nakata K, Sasaki K, Watanabe K, Nakashima K, Urakami K, Ooya T, Takahashi M, Yuzuriha T, Serikawa K, Yoshimoto S, Nakagawa R, Saito Y, Hatsuta H, Murayama S, Kakita A, Takahashi H, Yamaguchi H, Akazawa K, Kanazawa I, Ihara Y, Ikeuchi T, Kuwano R. | J Alzheimers Dis 41(4):1031-8, 2014 |
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5 | Transcriptome analysis of distinct mouse strains reveals kinesin light chain-1 splicing as an amyloid-β accumulation modifier. | Morihara T, Hayashi N, Yokokoji M, Akatsu H, Silverman MA, Kimura N, Sato M, Saito Y, Suzuki T, Yanagida K, Kodama TS,Tanaka T, Okochi M, Tagami S, Kazui H, Kudo T, Hashimoto R, Itoh N, Nishitomi K, Yamaguchi-Kabata Y, Tsunoda T,Takamura H, Katayama T, Kimura R, Kamino K, Hashizume Y, Takeda M. | Proc Natl Acad Sci U S A. 111(7): 2638-43, 2014 |
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2013 | 1 | An observational study of insomnia and nightmare treated with Trazodone in patients with advanced cancer. | Tanimukai H, Murai T, Okazaki N, Matsuda Y, Okamoto Y, Kabeshita Y, Ohno Y, Tsuneto S | Am J Hosp Palliat Care 30(4): 359 - 362, 2013 |
2 | Can gradual dose titration of Ketamine for management of neuropathic pain prevent psychotomimetic effects in patients with advanced cancer? | Okamoto Y, Tsuneto S, Tanimukai H, Matsuda Y, Ohno Y, Tsugane M, Uejima E | Am J Hosp Palliat Care 30(5): 450-454, 2013 |
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3 | Involvement of endoplasmic reticulum stress in tauopathy | Sakagami Y, Kudo T, Tanimukai H, Kanayama D, Omi T, Horiguchi K, Okochi M, Imaizumi K, Takeda M | Biochem Biophys Res Commun 430(2):500-4, 2013 |
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4 | Paclitaxel induces neurotoxicity through endoplasmic reticulum stress | Tanimukai H, Kanayama D, Omi T, Takeda M, Kudo T | Biochem Biophys Res Commun 437(1):151-155, 2013 |
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5 | γ-secretase modulators and presenilin 1 mutants act differently on presenilin/γ-secretase function to cleave Aβ42 and Aβ43 | Okochi M, Tagami S, Yanagida K, Takami M, Kodama TS, Mori K, Nakayama T, Ihara Y, Takeda M |
Cell Rep 3(1): 42-51,2013 |
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6 | Understanding the conflicting demands of family caregivers caring for depressed family members | Yamashita N, Kuzuoka H, Hirata K, Kudo T | CHI2013: 2637-2646, 2013 |
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7 | Inge Grundke-Iqbal, Ph.D. (1937-2012): the Discoverer of the Abnormal Hyperphosphorylation of Tau in Alzheimer's Disease | Alonso CA, Ekkard E, Gong CX, Liu F, Tanaka T, Kudo T, Tatebayashi Y, Pei JJ, Wang JZ, Khatoon S, Flory M, Ghetti B, Gozes I, Novak M, Novak M, Robakis NK, Leon M, Iqbal M | J Mol Neurosci DOI 10.1007/ ]s12031-012-9925-z, 2013 |
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8 | Role of endoplasmic reticulum stress in light-induced photoreceptor degeneration in mice | Nakanishi T, Shimazawa M, Sugitani S, Kudo T, Imai S, Inokuchi Y, Tsuruma K, Hara H | J Neurochem 125(1):111-124, 2013 |
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9 | Two advanced cancer patients in whom escitalopram was useful for depression | Nakajima S,Tanimukai H,Baba M,Amano K, awasaki M,Wakayama H | Palliative Care Research 8(2): 548-553, 2013 |
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10 | SORL1 Is Genetically Associated with Late-Onset Alzheimer's Disease in Japanese, Koreans and Caucasians | Miyashita A, Koike A, Jun G, Wang LS, Takahashi S, Matsubara E, Kawarabayashi T, Shoji M, Tomita N, Arai H, Asada T, Harigaya Y, Ikeda M, Amari M, Hanyu H, Higuchi S, Ikeuchi T, Nishizawa M, Suga M, Kawase Y, Akatsu H, Kosaka K, Yamamoto T, Imagawa M, Hamaguchi T, Yamada M, Morihara T, Takeda M, Takao T, Nakata K, Fujisawa Y, Sasaki K, Watanabe K, Nakashima K, Urakami K, Ooya T, Takahashi M, Yuzuriha T, Serikawa K, Yoshimoto S, Nakagawa R, Kim JW, Ki CS, Won HH, Na DL, Seo SW, Mook-Jung I; The Alzheimer Disease Genetics Consortium, St George-Hyslop P, Mayeux R, Haines JL, Pericak-Vance MA, Yoshida M, Nishida N, Tokunaga K, Yamamoto K, Tsuji S, Kanazawa I, Ihara Y, Schellenberg GD, Farrer LA, Kuwano R | PLoS One 8(7). doi:10.1371/ annotation/ fcb56ea7- d32a-4e45-818d- 39cef330c731, 2013 |
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2012 | 1 | A Retrospective Chart Review of Terminal Patients with Cancer with Agitation and Their Risk Factors | Nagase M, Okamoto Y, Tsuneto S, Tanimukai H, Matsuda Y, Okishiro N, Oono Y, Tsugane M, Takagi T, Uejima E | J Palliat Med 15(11): 1185-1190, 2012 |
2 | Non-pharmacological intervention for dementia patients. | Takeda M, Tanaka T, Okochi M, Kazui H | Psychiatry Clin Neurosci 66(1): 1-7,2012 |
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2011 | 1 | Molecular pathology of tauopathy and fronto temporal lobar degeneration: accumulation and aggregation of tau protein in tauopathies | Tanaka T, Sadik G, Yanagi K, Kato K, Takeda M | Asian J Psychiatr 4(Suppl.1) S1-S96, 2011 |
2 | Pharmacogenomics of Alzheimer disease | Takeda M, Martinez R, Kudo T, Tanaka T, Okochi M, Tagami S, Morihara T, Hashimoto R, Cacabelos R | Asia-Pacific Psychiatry 3; 10-6, 2011 |
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3 | Sigma-1Rs are upregulated via PERK/eIF2α/ATF4 pathway and execute protective function in ER stress | Mitsuda T, Omi T, Tanimukai H, Sakagami Y, Tagami S, Okochi M, Kudo T, Takeda M | Biochem Biophys Res Commun 415(3):519-25, 2011 |
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4 | Gender difference in psychogeriatric disorders | Takeda M, Tanaka T, Kudo T | Geriatr Gerontol Int11:377-82, 2011 |
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5 | Involvement of puromycin-sensitve aminopeptidase in metabolism of tau protein in cultured cells | Tanaka T, Yanagi K, Maruyama D, Takeda M | Int Psychogeriatr 23(Suppl.1): S281-282, 2011 |
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6 | President's Message | Takeda M | IPA Bulletin 28(1), 2011 | |
7 | President's Message | Takeda M | IPA Bulletin 28(2), 2011 | |
8 | Can milnacipran used for neuropathic pain in patients with advanced cancer cause neuromuscular and somatosensory disorders? | Nakagawa S, Okamoto Y, Tsuneto S, Tanimukai H, Goya S, Matsuda Y, Oono Y, Tsugane M, Uejima E | J Palliat Med 14(4):403-5. 2011 |
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9 | ENU-induced missense mutation in the C-propeptide coding region of Col2a1 creates a mouse of platyspondylic lethal skeletal dysplasia, Torrance type | Furuichi T, Masuya H, Murakami T, Nishida K, Nishimura G, Suzuki T, Imaizumi K, Kudo T, Ohkawa K, Wakana S, Ikegawa S | Mamm Genome 22(5-6):318-28, 2011 |
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10 | Association between CAG repeat length in the PPP2R2B gene and Alzheimer disease in the Japanese population | Kimura R, Morihara T, Kudo T, Kamino K, Takeda M | Neurosci Let487:354-57, 2011 |
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11 | Association between CAG repeat length in the PPP2R2B gene and Alzheimer disease in the Japanese population | Kimura R, Morihara T, Kudo T, Kamino K, Takeda M | Neurosci Lett487(3):354-7, 2011 |
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12 | Restraint-induced expression of endoplasmic reticulum stress-related genes in the mouse brain | Ishisaka M, Kudo T, Shimazawa M, Kakefuda K, Oyagi A, Hyakkoku K, Tsuruma K, Hara H | Pharmacology & Pharmacy 2(1): 10-6, 2011 |
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13 | Mental health care and east Japan great earthquake | Takeda M | Psychiatry Clin Neurosci 65: 207-12, 2011 |
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14 | New drugs for Alzheimer's disease in Japan | Takeda M, Tanaka T, Okochi M | Psychiatry Clin Neurosci 65(5): 399-404, 2011 |
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15 | Elderly depression and diffusion tensor imaging | Takeda M, Tanaka T, Kudo T | Psychogeriatrics11 (1):1-5, 2011 |
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16 | Protein kinase C stabilizes X-linked inhibitor of apoptosis protein (XIAP) through phosphorylation at Ser(87) to suppress apoptotic cell death | Kato K, Tanaka T, Sadik G, Baba M, Maruyama D, Yanagida K, Kodama T, Morihara T, Tagami S, Okochi M, Kudo T, Takeda M | Psychogeriatrics 11(2):90-7, 2011 |
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17 | The great eastern Japan earthquake and psychogeriatric services | Takeda M, Tanaka T | Psychogeriatrics11 (4):191-95,2011 |